Prof Willie Hamilton
Director (Research)
Willie co-leads CanTest with Fiona Walter. The responsibilities have been split such that Willie leads on the research aspects, whilst Fiona leads on faculty.
A GP and lead of the DISCOVERY group in Exeter, Willie was also clinical lead for the 2015 NICE guidance, as well as being a member of the Department of Health’s Policy Research Unit for cancer awareness, screening and early diagnosis.
Willie has been working on early cancer diagnosis for over twenty years. This began with studies that sought to identify and quantify the important features of cancer in a GP’s consulting room. This proceeded on a cancer site-by-site basis and mapped out the important features of colorectal cancer, then of lung, etc. Individual features were then tackled, e.g. what were the cancer risks from a raised calcium level or from thrombocytosis. Work then moved on to implementation, with adaptation of the teams outputs to GP computer systems and supporting NICE in collating NG12, the massive guidance on cancer investigation. This ongoing work has been supported by research grants from NIHR, CRUK, the Department of Health, and other charities.
Willie has won the cancer Research Paper of the Year several times, and the Overall Research Paper of the Year twice. He was awarded a CBE for improving cancer diagnosis in 2019.
Follow Willie on Twitter @BoomboomchiefsT
+44 (0)7825 122330
University of Exeter, UK
Early diagnosis, at a local and at a system level
- Multi-parametric magnetic resonance imaging (mpMRI) for prostate cancer diagnosis in primary care
- International comparison of FIT use across the globe in primary care symptomatic patients: A narrative view
- Establishing the diagnostic accuracy of haemoglobin in faecal immunochemical tests (FITs) and establishing a receiver operating characteristic (ROC) curve for FITs in the English primary care symptomatic population: A cohort study in the South West of England
- Establishing the diagnostic accuracy, acceptability and cost-effectiveness of haemoglobin in faecal immunochemical tests (FITs) in the English primary care symptomatic population: a cohort study in the East of England
- Understanding missed diagnostic opportunities in bladder and kidney cancer
- What is the clinical-effectiveness and cost-effectiveness of embedded risk-of-cancer assessment of patients in primary care; the ERICA trial
- The role of imaging in the diagnosis of symptomatic lung cancer
- The diagnostic utility of inflammatory markers in primary care: a prospective cohort study
- Tests and tools for the detection of ovarian cancer in primary care
- Abdominal pain in primary care: establishing a clinical profile and diagnostic pathway for identifying cancer
- Evaluating the impact of NICE guidelines for suspected cancers in respect of diagnostic interval and other outcomes
- Aids to cancer diagnosis in primary care
- Are patients with high normal platelet counts at increased risk of cancer?
- Guideline discordant diagnostic care: when do referrals not reflect guidelines for suspected cancer?
- Exploring patient, practitioner and general population preferences towards diagnostic tests for cancer
- Risk of lung cancer in symptomatic patients with negative chest x-ray results
- Impact of decision tools for early cancer diagnosis in general practice on GP workload and patient ‘flow’ during consulting sessions (PhD)
- What factors influence GPs’ decision to request imaging for possible lung cancer?
- Establishing which modalities of artificial intelligence machine learning (AI/ML) for early detection and diagnosis of cancer are ready for implementation in primary care in the NHS: a Systematic Review
- Diagnostic accuracy of FIT in patients urgently referred for colorectal cancer
- Is General Practice chest x-ray rate associated with lung cancer outcomes?
- Wales Interventions and Cancer Knowledge about Early Diagnosis
- Achieving earlier cancer diagnosis in primary care using routine blood test results: a study using US healthcare claims data
- Exploring the molecular mechanisms underlying pre-diagnostic thrombocytosis in lung cancer patients and evaluating its diagnostic value (PhD)
- Exploring the complex relationships between pre-existing conditions and cancer diagnosis in an ageing population
- Are common blood tests being optimally used for early cancer diagnosis? (PhD)
- Exploring the complex relationships between pre-existing conditions and cancer diagnosis in an ageing population (PhD)
- Investigating the impact of changes in the NHS in response to the COVID-19 crisis on cancer diagnosis in the South West of England
- CanImpact: the impact of the COVID-19 pandemic on cancer detection in primary care
- Examining methodology to identify patterns of consulting in primary care for different groups of patients before a diagnosis of cancer: a matched retrospective cohort study
- Investigating the use of routine blood tests and reflex testing to improve the early diagnosis of myeloma
- SPOtting Cancer among Comorbidities (SPOCC) programme: Supporting clinical decision making in patients with symptoms of cancer and pre-existing conditions
- Evaluating ethnic differences in blood markers of cancer in primary care
- Investigating the conversion rate of routine referrals for patients presenting with symptoms of possible cancer
- Urgent referrals for suspected cancer in England 2009/10-2019/20: temporal trend analysis of population-based routine data
- Ozawa M, Brennan PM, Zienius K, Kurian KM, Hollingworth W, Weller D, Hamilton W, Grant R, Ben-Shlomo Y. Symptoms in primary care with time to diagnosis of brain tumours. Family Practice, 2018: 1-8
- Stanciu MA, Law R-J, Nafees S, Hendry M, Yeo ST, Hiscock J, Lewis R, Edwards RT, Williams NH, Brain K, Brocklehurst P, Carson-Stevens A, Dolwani S, Emery J, Hamilton W, Hoare Z, Lyratzopoulos G, Rubin G, Smits S, Vedsted P, Walter FM, Wilkinson C, Neal RD. Development of an intervention to expedite cancer diagnosis through primary care: Protocol. BJGP Open 4 September 2018; bjgpopen18X101595
- Renzi C, Lyratzopoulos G, Hamilton W, Rachet B. Opportunities for reducing emergency diagnoses of colon cancer in women and men: a data-linkage study on pre-diagnostic symptomatic presentations and benign diagnoses. Eur Journal Cancer Care. 2019. e13000. doi: 10.1111/ecc.13000
- Mendonca SC, Abel GA, Gildea C, McPhail S, Peake MD, Rubin G, Singh H, Hamilton W, Walter FM, Roland MO, Lyratzopoulos G. Associations between general practice characteristics with use of urgent referrals for suspected cancer and endoscopies: a cross-sectional ecological study. Family Practice, 2018, cmy118
- Walter FM, Penfold C, Joannides A, Saji S, Johnson M, Watts C, Brodbelt A, Jenkinson MD, Price SJ, Hamilton W, Scott SE. Missed opportunities for diagnosing brain tumours in primary care: a qualitative study of patient experiences. Br J Gen Pract, 2019, bjgp19X701861. DOI: 10.3399/bjgp19X70186
- Scott SE, Penfold C, Saji S, Curtis S, Watts C, Hamilton W, Joannides AJ, Walter FM. ‘It was nothing that you would think was anything’: Qualitative analysis of appraisal and help seeking preceding brain cancer diagnosis. PLoS ONE, 2019, 14:3, e02135
- Zhou Y, Funston G, Lyratzopoulos G, Walter FM. Improving the Timely Detection of Bladder and Kidney Cancer in Primary Care. Advances in Therapy, 2019. doi: 10.1007/s12325-019-00966-x
- Watson J, Salisbury C, Banks J, Whiting P, Hamilton W. Predictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records. British Journal of Cancer, 2019, 120:1045-1051
- Walter FM, Thompson MJ, Wellwood I, Abel GA, Hamilton W, Johnson M, Lyratzopoulos G, Messenger MP, Neal RD, Rubin G, Singh H, Spencer A, Sutton S, Vedstead P, Emery JD. Evaluating diagnostic strategies for early detection of cancer: the CanTest framework. BMC Cancer, 2019, 19:586
- Renzi C, Kaushal A, Emery J, Hamilton W, Neal RD, Rachet B, Rubin G, Singh H, Walter FM, de Wit NJ, Lyratzopoulos G. Comorbid chronic diseases and cancer diagnosis: disease-specific effects and underlying mechanisms. Nature Reviews: Clinical Oncology, 2019, doi: 10.1038/s41571-019-0249-6
- Merriel SWD, Hardy V, Thompson M, Walter FM, Hamilton W. Patient-centered outcomes from multiparametric magnetic resonance imaging (mpMRI) and MRI-guided biopsy for prostate cancer: A systematic review. Journal of the American College of Radiology, 2019, S1546-1440(19)31032-4
- Zhou Y, van Melle M, Singh H, Hamilton W, Lyratzopoulos G, Walter FM. Quality of the Diagnostic Process in Patients Presenting with Symptoms Suggestive of Bladder or Kidney Cancer: A Systematic Review. British Medical Journal Open, 2019, 2019;9:e029143. doi: 10.1136/bmjopen-2019-029143
- Nicholson BD, Aveyard P, Hamilton W, Hobbs FDR. When should unexpected weight loss warrant further investigation to exclude cancer? British Medical Journal, 2019, 366:l5271, doi: 10.1136/bmj.l5271
- Watson J, Mounce L, Bailey SER, Cooper SL, Hamilton W. Blood markers for cancer. British Medical Journal, 2019, 367:l5774, doi: 10.1136/bmj.l5774
- Funston G, Van Melle M, Ladegaard Baun M-L, Jensen H, Helsper C, Emery J, Crosbie EJ, Thompson M, Hamilton W, Walter F. Variation in the initial assessment and investigation for ovarian cancer in symptomatic women: a systematic review of international guidelines. BMC Cancer, 2019, 19:1028 doi:10.1186/s12885-019-6211-2
- Chowienczyk S, Price S, Hamilton W. Changes in the presenting symptoms of lung cancer from 2000–2017: a serial cross-sectional study of observational records in UK primary care. British Journal of General Practice, 2020, doi: 10.3399/bjgp20X708137
- Pearson C, Poirier V, Fitzgerald K, Rubin G, Hamilton W. Cross-sectional study using primary care and cancer registration data to investigate patients with cancer presenting with non-specific symptoms. BMJ Open, 2020, doi: 10.1136/bmjopen-2019-033008
- Watson J, Jones HE, Banks J, Whiting P, Salisbury C, Hamilton W. Use of multiple inflammatory marker tests in primary care: using Clinical Practice Research Datalink to evaluate accuracy. British Journal of General Practice, 2019, doi: 10.3399/bjgp19X704309
- Watson J, Salisbury C, Whiting P, Banks J, Pyne Y, Hamilton W. Added value and cascade effects of inflammatory marker tests in UK primary care: a cohort study from the Clinical Practice Research Datalink. British Journal of General Practice, 2019, doi: 10.3399/bjgp19X704321
- Zhou Y, Abel GA, Hamilton W, Singh H, Walter FM, Lyratzopoulos G. Imaging activity possibly signalling missed diagnostic opportunities in bladder and kidney cancer: A longitudinal data-linkage study using primary care electronic health records. Cancer Epidemiology, 2020, doi: 10.1016/j.canep.2020.101703
- van Melle M, Yep Manzano S, Wilson H, Hamilton W, Walter FM, Bailey SER. Faecal immunochemical test to triage patients with abdominal symptoms for suspected colorectal cancer in primary care: review of international use and guidelines. Family Practice, 2020. doi: 10.1093/fampra/cmaa043
- Carney M, Quiroga M, Mounce L, Shephard E, Hamilton W, Price S. Effect of pre-existing conditions on bladder cancer stage at diagnosis: a cohort study using electronic primary care records in the UK. British Journal of General Practice, 2020. doi: 10.3399/bjgp20X710921
- Hopkins R, Bailey SER, Hamilton WT, Shephard EA. Microcytosis as a risk marker of cancer in primary care: a cohort study using electronic patient records. British Journal of General Practice, 2020; 70 (696): e457-e462. doi: 10.3399/bjgp20X709577
- Jones OT, Calanzani N, Saji S, Duffy SW, Emery J, Hamilton W, Singh H, de Wit N, Walter F. Application of artificial intelligence to electronic health records for early detection and diagnosis of cancer in primary care: a Systematic Review. JMIR, 2020:23483, doi: 10.2196/preprints.23483
- Mounce LTA, Hamilton W, Bailey SER. Cancer incidence following a high-normal platelet count: cohort study using electronic healthcare records from English primary care. British Journal of General Practice, 2020, doi: 10.3399/bjgp20X710957
- Chapman D, Poirier V, Vulkan D, Fitzgerald K, Rubin G, Hamilton W, Duffy SW. First results from five multidisciplinary diagnostic centre (MDC) projects for non-specific but concerning symptoms, possibly indicative of cancer. British Journal of Cancer, 2020, doi: 10.1038/s41416-020-0947-y
- Nicholson BD, Hamilton W, Koshiaris C, Oke JL, Hobbs R, Aveyard P. The association between unexpected weight loss and cancer diagnosis in primary care: a matched cohort analysis of 65,000 presentations. British Journal of Cancer, 2020, 122(12): 1848-1856, doi: 10.1038/s41416-020-0829-3
- Price S, Spencer A, Zhang X, Ball S, Lyratzopoulos, Mujica-Mota R, Stapley S, Ukoumunne OC, Hamilton W. Trends in time to cancer diagnosis around the period of changing national guidance on referral of symptomatic patients: A serial cross-sectional study using UK electronic healthcare records from 2006–17. Cancer Epidemiology, 2020; 101805, doi: 10.1016/j.canep.2020.101805
- Funston G, Hamilton W, Abel G, Crosbie EJ, Rous B, Walter FM (2020) The diagnostic performance of CA125 for the detection of ovarian and non-ovarian cancer in primary care: A population-based cohort study. PLoS Med 17(10): e1003295. doi:10.1371/journal.pmed.1003295
- Clarke C, Hamilton W, Price S, Bailey SER. Association of non-malignant diseases with thrombocytosis: a prospective cohort study in general practice. British Journal of General Practice, 2020, 70(701): e852-e857, doi: 10.3399/bjgp20X713501
- Funston G, Hardy V, Abel, G, Crosbie EJ, Emery J, Hamilton W, Walter FM. Identifying Ovarian Cancer in Symptomatic Women: A Systematic Review of Clinical Tools. Cancers 2020, 12, 3686. doi: 10.3390/cancers12123686
- Arendse KD, Walter FM, Pilling M, Zhou Y, Hamilton W, Funston G. Time from presentation to pre-diagnostic chest X-ray in symptomatic lung cancer patients: a cohort study using electronic patient records. British Journal of General Practice, 2020, bjgp20X714077, doi: 10.3399/bjgp20X714077
- Bailey SER, Abel GA, Atkins A, Byford R, Davies S-J, Mays J, McDonald TJ, Miller J, Neck C, Rennison J, Thomas P, Walter FM, Warren S, Hamilton W. Diagnostic performance of a faecal immunochemical test for patients with low-risk symptoms of colorectal cancer in primary care: an evaluation in the South West of England. British Journal of Cancer, 2021, doi: 10.1038/s41416-020-01221-9
- Zhou Y, Walter FM, Singh H, Hamilton W, Abel GA, Lyratzopoulos. Prolonged Diagnostic Intervals as Marker of Missed Diagnostic Opportunities in Bladder and Kidney Cancer Patients with Alarm Features: A Longitudinal Linked Data Study. Cancers, 2021, 13(1): 156, doi: 10.3390/cancers13010156
- Jones OT, Calanzani N, Saji S, Duffy SW, Emery J, Hamilton W, Singh H, de Wit NJ, Walter FM. Artificial Intelligence Techniques That May Be Applied to Primary Care Data to Facilitate Earlier Diagnosis of Cancer: Systematic Review. J Med Internet Res, 2021;23(3):e23483. doi: 10.2196/23483
- Funston G, Mounce LTA, Price S, Rous B, Crosbie EJ, Hamilton W, Walter FM. CA125 test result, test-to-diagnosis interval and stage in ovarian cancer: a cohort study using electronic health records. BJGP, doi: 10.3399/BJGP.2020.0859
- Martins T, Merriel SWD, Hamilton W. Routes to diagnosis of symptomatic cancer in sub-Saharan Africa: systematic review. BMJ Open, 2020;10:e038605. doi: 10.1136/bmjopen-2020-038605
- Quiroga M, Shephard EA, Mounce LTA, Carney M, Hamilton WT, Price SJ. Quantifying the impact of pre-existing conditions on the stage of oesophagogastric cancer at diagnosis: a primary care cohort study using electronic medical records. Family Practice, 2020, doi: 10.1093/fampra/cmaa132
- Bradley SH, Hatton NLF, Aslam R, Bhartia B, Callister MEJ, Kennedy MPT, Mounce L, Shinkins B, Hamilton WT, Neal RD. Estimating lung cancer risk from chest x-ray and symptoms: a prospective cohort study. British Journal of General Practice, 2020, doi: 10.3399/bjgp20X713993
- Keeney E, Mohiuddin S, Zienius K, Ben-Shlomo Y, Ozawa M, Grant R, Hamilton W, Weller D, Brennan PM, Hollingworth W. Economic evaluation of GPs’ direct access to computed tomography for identification of brain tumours. European Journal of Cancer Care, 2020, doi: 10.1111/ecc.13345
- Merriel SWD, Hamilton W. Improving early cancer diagnosis in primary care. Prescriber, 2020, 31:9, 10-14, doi: 10.1002/psb.1862
- Baun ML, Dueholm M, Heje HN, Hamilton W, Petersen LK, Vedsted P. Direct access from general practice to transvaginal ultrasound for early detection of ovarian cancer: a feasibility study. Scandinavian Journal of Primary Care Health, 2021, doi: 10.1080/02813432.2021.1922831
- Nicholson BD, Aveyard P, Koshiaris C, Perera R, Hamilton W, Oke J, Hobbs FDR. Combining simple blood tests to identify primary care patients with unexpected weight loss for cancer investigation: Clinical risk score development, internal validation, and net benefit analysis. PLoS Med, 2021 18(8): e1003728. doi: 10.1371/journal.pmed.1003728
- Bhartia B.S.K, Hatton N, Aslam R, Bradley SH, Darby M, Hamilton W, Hurst E, Kennedy M.P.T, Mounce L.T.A., Neal R.D., Shinkins B, Callister M.E.J. A prospective cohort evaluation of the sensitivity and specificity of the chest X-ray for the detection of lung cancer in symptomatic adults. European Journal of Radiology, 2021, doi.org/10.1016/j.ejrad.2021.109953.
- Bradley SH, Bhartia BS, Callister ME, Hamilton WT, Hatton NLF, Kennedy MP, Mounce L, Shinkins B, Neal R, et al. Chest X-ray sensitivity and lung cancer outcomes: a retrospective observational study. British Journal of General Practice, 2021. doi: 10.3399/BJGP.2020.1099
- Chapman D, Poirier V, Fitzgerald K, Nicholson BD, Hamilton W. Non-specific symptoms-based pathways for diagnosing less common cancers in primary care: a service evaluation. British Journal of General Practice, 2021 doi:10.3399/BJGP.2020.1108
- Funston G, Abel G, Crosbie EJ, Hamilton W, Walter FM. Could Ovarian Cancer Prediction Models Improve the Triage of Symptomatic Women in Primary Care? A Modelling Study Using Routinely Collected Data. Cancers, 2021. doi:10.3390/cancers13122886
- Funston G, Mounce LTA, Price S, Rous B, Crosbie EJ, Hamilton W, Walter FM. CA125 test result, test-to-diagnosis interval, and stage in ovarian cancer at diagnosis: a retrospective cohort study using electronic health records. British Journal of General Practice, 2021; 71 (707): e465-e472. DOI: 10.3399/BJGP.2020.0859
- Martins T, Walter FM, Penfold C, Abel G, Hamilton W. Primary care use by men with symptoms of possible prostate cancer: A multi-method study with an ethnically diverse sample in London. European journal of cancer care, 2021. doi:10.1111/ecc.13482
- Price S, Abel GA, Hamilton W. Guideline interval: A new time interval in the diagnostic pathway for symptomatic cancer. Cancer Epidemiology, 2021; volume 73, 2021, 101969, ISSN 1877-7821. doi:10.1016/j.canep.2021.101969
- Rubin G, Walter FM, Emery J, Hamilton W, Hoare Z, Howse J, Nixon C, Srivastava T, Thomas C, Ukoumunne OC, Usher-Smith JA, Whyte S, Neal RD. Electronic clinical decision support tool for assessing stomach symptoms in primary care (ECASS): a feasibility study. BMJ Open, 2021;11:e041795. doi: 10.1136/bmjopen-2020-041795
- White B, Rafiq M, Gonzalez-Izquierdo A, Hamilton W, Price S, Lyratzopoulos G. Risk of cancer following primary care presentation with fatigue: A population-based cohort study of a quarter of a million patients. Br J Cancer (2022). doi: 10.1038/s41416-022-01733- 6
- Price S, Gibson N, Hamilton W, King A, Shephard E. Intra-abdominal cancer risk with abdominal pain: a prospective cohort primary-care study. British Journal of General Practice. Feb 2022 .2021.0552. doi: 10.3399/BJGP.2021.0552
- Merriel SWD, Pocock L, Gilbert E, Creavin S, Walter FM, Spencer A, Hamilton W. Systematic review and meta-analysis of the diagnostic accuracy of prostate-specific antigen (PSA) for the detection of prostate cancer in symptomatic patients. BMC Med 20, 54 (2022). doi: 10.1186/s12916-021-02230-y
- Hall R, Medina-Lara A, Hamilton W, Spencer A. Attributes Used for Cancer Screening Discrete Choice Experiments: A Systematic Review. Patient (2021). doi: 10.1007/s40271-021-00559-3
- Hall R, Medina-Lara A, Hamilton W, Spencer A. Correction to: Attributes Used for Cancer Screening Discrete Choice Experiments: A Systematic Review. Patient (2021). doi: 10.1007/s40271-021-00562-8
- Barlow M, Hamilton W, Ukoumunne O, Bailey S. (2021). The association between thrombocytosis and subtype of lung cancer: a systematic review and meta-analysis. Translational Cancer Research, 10(3), 1249-1260. doi: 10.21037/tcr-20-3287
- Smith S, Sansom N, Hemphill S, Bradley SH, Shinkins B, Wheatstone P, Hamilton W, Neal RD. Trends and variation in urgent referrals for suspected cancer 2009/2010–2019/2020, British Journal of General Practice 2022; 72 (714): 34-37. doi: 10.3399/bjgp22X718217
- Offman, J, Pesola, F, Fitzgerald, RC, Hamilton, W, Sasieni, P. Impact of Barrett oesophagus diagnoses and endoscopies on oesophageal cancer survival in the UK: A cohort study. Cancer Med. 2021; 00: 1– 12. doi: 10.1002/cam4.4484
- Zhou Y, Walter FM, Mounce L, Abel GA, Singh H, Hamilton W, Stewart GD, Lyratzopoulos G. Identifying opportunities for timely diagnosis of bladder and renal cancer via abnormal blood tests: a longitudinal linked data study. British Journal of General Practice. Dec 2021; doi: 10.3399/BJGP.2021.0282
- Wiering B, Lyratzopoulos G, Hamilton W, et al. Concordance with urgent referral guidelines in patients presenting with any of six ‘alarm’ features of possible cancer: a retrospective cohort study using linked primary care records. BMJ Quality & Safety. 04 October 2021. doi: 10.1136/bmjqs-2021-013425
- Martins T, Abel G, Ukoumunne OC, Mounce LTA, Price S, Lyratzopoulos G, Chinegwundoh F, Hamilton W. Ethnic inequalities in routes to diagnosis of cancer: A population-based UK cohort study. Br J Cancer (2022). doi: 10.1038/s41416-022-01847-x
- Hall R, Medina-Lara A, Hamilton W, Spencer A. Women’s priorities towards ovarian cancer testing: a best–worst scaling study. BMJ Open (2022); 12:e061625. doi: 10.1136/bmjopen-2022-061625
- Funston G, Crosbie EJ, Hamilton W, Walter FM. Detecting ovarian cancer in primary care: can we do better? British Journal of General Practice 2022; 72 (720): 312-313. doi: 10.3399/bjgp22X719825
- White B, Rafiq M, Gonzalez-Izquierdo A, Hamilton W, Price S, Lyratzopoulos G. Risk of cancer following primary care presentation with fatigue: A population-based cohort study of a quarter of a million patients. Br J Cancer (2022). doi: 10.1038/s41416-022-01733- 6
- Merriel SWD, Ball S, Bright CJ, Mak V, Gildea C, Paley L, Hyde C, Hamilton W, Elliss-Brookes L. (2022). A prospective evaluation of the fourth national Be Clear on Cancer ‘Blood in Pee’ campaign in England. European Journal of Cancer Care, 1– 11. doi: 10.1111/ecc.13606
- Price S, Landa P, Mujica-Mota R, Hamilton W, Spencer A. Revising the Suspected-Cancer Guidelines: Impacts on Patients’ Primary Care Contacts and Costs. Value in Health, Aug 2022.
doi: 10.1016/j.jval.2022.06.017 - Merriel SWD, Archer S, Forster AS, Eldred-Evans D, McGrath J, Ahmed HU, Hamilton W, Walter FM. Experiences of ‘traditional’ and ‘one-stop’ MRI-based prostate cancer diagnostic pathways in England: a qualitative study with patients and GPs. BMJ Open 2022; 12:e054045. doi: 10.1136/bmjopen-2021-054045
- Martins T, Abel G, Ukoumunne OC, Price S, Lyratzopoulos G, Chinegwundoh F, Hamilton W. Assessing Ethnic Inequalities in Diagnostic Interval of Common Cancers: A Population-Based UK Cohort Study. Cancers 2022; 14(13):3085. doi: 10.3390/cancers14133085
- Calanzani N, Pannebakker MM, Tagg MJ, Walford H, Holloway P, de Wit N, Hamilton W, Walter FM. Who are the patients being offered the faecal immunochemical test in routine English general practice, and for what symptoms? A prospective descriptive study. BMJ Open 2022; 12:e066051. doi: 10.1136/bmjopen-2022-066051
- O’Dowd EL, ten Haaf K, Kaur J, Duffy SW, Hamilton W, Hubbard RB, Field JK, Callister MEJ, Janes SM, de Koning HJ, Rawlinson J, Baldwin DR. Selection of eligible participants for screening for lung cancer using primary care data. Thorax 2022; 77:882-890. doi: 10.1136/thoraxjnl-2021-217142
- Black GB, van Os S, Renzi C, Walter FM, Hamilton W, Whitaker KL. How does safety netting for lung cancer symptoms help patients to reconsult appropriately? A qualitative study. BMC Prim. Care 23, 179 2022. doi: 10.1186/s12875-022-01791-y
- Watson J, Whiting PF, Salisbury C, Hamilton WT, Banks J. Blood tests in primary care: A qualitative study of communication and decision-making between doctors and patients. Health Expectations Jul 2022. doi: 10.1111/hex.13564
- Watson J, Salisbury C, Whiting PF, Hamilton WT, Jonathan Banks. ‘I guess I’ll wait to hear’— communication of blood test results in primary care a qualitative study. British Journal of General Practice 2022; 72 (723): e747-e754. doi: 10.3399/BJGP.2022.0069
- Price S, Gibson N, Hamilton W, Bostock J, Shephard E. Diagnoses after newly-recorded abdominal pain in primary care: observational cohort study. British Journal of General Practice April 2022; BJGP.2021.0709. doi: 10.3399/BJGP.2021.0709
- Briggs E, de Kamps M, Hamilton W, Johnson O, McInerney CD, Neal RD. Machine Learning for Risk Prediction of Oesophago-Gastric Cancer in Primary Care: Comparison with Existing Risk-Assessment Tools. Cancers. 2022; 14(20):5023. doi: 10.3390/cancers14205023